OCS is a powerful and flexible tool for managing software deployments. It provides a simple and efficient way to manage software installation, updates, and script execution on remote systems.
The TransMedics Organ Care System (OCS) heart is a portable ex vivo perfusion system that allows donor hearts to be preserved longer than SherpaPak or SCS. This extended preservation time can potentially increase the pool of available donors.
It monitors the heart’s function
The OCS heart system is a portable extracorporeal warm perfusion and assessment device that keeps a donor’s heart in a normothermic, beating state. Its unique physiologic monitoring provides valuable information that can help physicians assess the quality of an organ’s function and viability for transplantation.
The heart’s ventricular pacing is established on the OCS machine by connecting the aortic cannula to its return spout and venting the pulmonary artery cannula in the OCS box cradle (Figure 3A). Once the heart starts beating, ventricular wires are placed to titrate coronary blood flow at a desired rate. Defibrillation pads are also available to shock the heart in case of fibrillation.
The OCS heart system can reduce cold ischemia time, which is one of the major risk factors for morbidity and mortality post-transplant. It also enables surgeons to perform real-time coronary angiography on the OCS system, which is the best way to diagnose significant graft stenosis. In addition, the OCS heart system can reassess organs from extended-criteria donors and DCD donors who have longer cold ischemic times.
It allows for the recovery of a heart
The TransMedics Organ Care System is a portable device that allows donor hearts to be preserved in a warm perfused oxygenated state. It is designed to minimize ischemia and optimize the heart for transplantation. A clinical study using this technology shows that 95 out of 100 donated hearts preserved with OCS were successfully transplanted.
The system also allows for a more thorough assessment of the donor heart by continuously monitoring aortic pressure and lactate levels. It can even determine whether a donor heart is a good fit for a recipient based on its coronary blood flow and graft function.
The traditional method of transporting organs is to use medical coolers, but these do not perform the functions that they would in a body. Using OCS, blood, oxygen and nutrients continuously flow through the organs, which prompts them to continue functioning. For example, the liver produces bile, one of its essential body functions. Consequently, this technique can potentially increase the number of donor hearts and reduce waiting list mortality.
It can be used for heart transplants
The OCS heart is an ex-vivo organ perfusion system that monitors and preserves donor hearts during transport. It allows hearts to be transported over longer distances than cold storage and is the only system that can be used for donation after circulatory death (DCD). It also enables heart transplantation of marginal donors with a low ejection fraction. This method may increase the donor pool and improve clinical outcomes.
The heart is placed in a specially designed tray and connected to the OCS system. The aorta is cross-clamped and 900 ml of Bretschneider cardioplegia is administered at a pressure of 180 mm Hg. The aortic and pulmonary cannulas are then connected to the spouts of the OCS heart, which drain directly into the reservoir.
During transportation, the OCS system continuously monitors physiologic parameters including coronary flow, aortic pressure, mixed venous hemoglobin saturation percentage, haematocrit percent, blood temperature and pulmonary artery pressure. It alerts the operator if any of these parameters are outside of the normal range.
It is portable
The OCS system is a Federally regulated safety system that is designed to turn off the passenger Advanced Front Air Bag for an empty seat or for occupants classified as being small, such as children. This helps to reduce the risk of injury or death in the event of an accident. If your passenger airbag status light remains illuminated, the OCS sensors may need to be serviced.
The 2-sensor OCS uses strain gauge type weight sensors to classify the occupant and turn OFF the passenger airbag under certain conditions described by U.S. regulations. These sensors are located on a portion of the front passenger seat frame assembly.
If you are experiencing issues with the 2-sensor OCS, verify the operation of the sensor with CONSULT. If the airbag light continues to flash, move the child into a rear seat and secure it with a safety restraint. Make sure that the seat belt is also used properly and positioned correctly. If the issue persists, you will need to contact your Nissan dealer for further support.